DEPENDABLE EXCELLENCE IN VECTOR-BORNE DIAGNOSTICS

Rickettsia Monoclonal Collections

 IMMUNOGEN       DESCRIPTION OF COLLECTION
 R. conorii OMP  10 clones reactive to rOmpB, some also against rOmpA, with varying      degrees of reactivity to other SFG species.
 R. rickettsii OMP   New: 2 clones reactive to rOmpB, undetermined reactivity against rOmpA, with varying degrees of reactivity to other SFG species.
 R. canadensis OMP  4 clones reactive to rOmpB and 1 clone against rOmpA, with negligable reactivity to SFG or TG species.
 R. akari OMP  21 clones reactive to rOmpB, some also against rOmpA, with varying degrees of reactivity to other SFG species.
 R. typhi OMP  31 clones reactive to rOmpB of R.typhi. Clones range from low-level to negligable reactivity to R. prowazekii.
 R. prowazekii  5 clones reactive to typhus group lipopolysaccharide antigen.
 SFG LPS  Direct conjugate of monoclonal anti-SFG LPS with Alexafluor 488 and Evans’ Blue counterstain.
Monoclonal antibody is sold as purified IgG in 100 microgram quanities, unless other arrangements are made. Please inquire for details and current prices.

This collection used s-layer (OmpA and OmpB) proteins from Rickettsia conorii conorii (Moroccan) as immunogen. The reactivities are mainly to closely related SFG species, although some closely related species (even conorii subspecies) are missing the appropriate epitope.


CLONE  TARGET  X-REACTIVITY  AVAILABILITY
 RC-1G9  rOmpB  conorii(caspia), slovaca, africae  IN STOCK
 RC-7H9  rOmpB+A  rickettsii, parkeri, montanensis  ASCITES
 RC-9C2  rOmpB  conorii (caspia, israelensis), africae, parkeri,  montanensis, honei, slovaca, others less reactive  IN STOCK
 RC-10F10  rOmpB  rickettsii, parkeri, montanensis,  ASCITES
 RC-5H7  rOmpB  parkeri, montanensis, slovaca  ASCITES
 RC-6E2  rOmpB  conorii (caspia), canadensis  ASCITES
 RC-3B6  rOmpB  honei, slovaca  3-5 WEEKS
 RC-1B12  rOmpB  conorii (indica)  ASCITES
 RC-7F5  rOmpB  conorii(caspia), canadensis  ASCITES
 RC-5H2  rOmpB+A  rickettsii, parkeri, montanensis  IN STOCK
Monoclonal antibody is prepared as purified IgG in 100 microgram quantities, unless other arrangements are made. If current inventory is ascitic fluid or cryopreserved cells, we will estimate the time necessary to produce these particular antibodies. Please inquire for details and current prices.

PAN-SFG RICKETTSIA MONOCLONAL

This clone was prepared with full s-layer, including the lipopolysaccharide (LPS). It reacts with the spotted fever group-specific LPS and is currently available for immunohistochemistry (IHC) and other uses where a widely-reactive mouse monoclonal produces clean staining.


CLONE             TARGET  X-REACTIVITY  AVAILABILITY
 RAK-9B8  LPS  reacts only with spotted fever group Rickettsia spp.  IN STOCK

Monoclonal antibody is currently available as ascites and purified IgG (1 mg or 100 ug). Please inquire for details and current prices.

RICKETTSIA CANADENSIS OMP COLLECTION

This collection used extracted outer-membrane proteins from Rickettsia canadensis (McKeil) as immunogen. All 5 clones react with both McKeil (2678) and CA410 strains.


  CLONE  TARGET  ISOTYPE  AVAILABILITY
  CA-2A4   rOmpB   IgG2b (lambda)  3-5 weeks
  CA-2H10   rOmpB   IgG2b (lambda)  3-5 weeks
  CA-3A2   rOmpA   IgG1 (kappa-1)  3-5 weeks
  CA-5D1   rOmpB   IgG2b (lambda)  3-5 weeks
  CA-6D1   rOmpB   IgG2b (lambda)  3-5 weeks

Monoclonal antibody is prepared as purified IgG in 100 microgram quanities, unless other arrangements are made. If current inventory is ascitic fluid or cryopreserved cells, we will estimate the time necessary to produce these particular antibodies. Please inquire for details and current prices.

SFG RICKETTSIA MONOCLONALS

This collection used s-layer (OmpA and OmpB) from Rickettsia akari (Kaplan) as immunogen. The reactivities are mainly to closely related SFG species, hence, very different than the clones raised against R. conorii conorii.


CLONE             TARGET  X-REACTIVITY  AVAILABILITY
 RAK-10D12  rOmpB    3-5 weeks
 RAK-10E3 (SDS-sens)    3-5 weeks
 RAK-1D3  rOmpB  helvetica, montanensis  3-5 weeks
 RAK-1E10  rOmpB  helvetica, massiliae  3-5 weeks
 RAK-1E4  rOmpB    3-5 weeks
 RAK-1E5 (SDS-sens)    3-5 weeks
 RAK-1G5  rOmpB  helvetica, montanensis  3-5 weeks
 RAK-1G6  rOmpB  helvetica, australis, tamurae, asiatica  3-5 weeks
 RAK-1H9  rOmpB+A  montanensis, massiliae, helvetica, tamurae, asiatica  3-5 weeks
 RAK-3A5  rOmpB+A    3-5 weeks
 RAK-3C4  rOmpB+A    3-5 weeks
 RAK-4C11  rOmpB    3-5 weeks
 RAK-5D10  rOmpB    3-5 weeks
 RAK-5F8  rOmpB  helvetica  3-5 weeks
 RAK-6F11  rOmpB  australis  3-5 weeks
 RAK-6G3  rOmpB+A    3-5 weeks
 RAK-8A9  rOmpB+A  helvetica, tamurae,asiatica,  3-5 weeks
 RAK-9A1  rOmpB+    3-5 weeks
 RAK-9B8    LPS  detects all SFG species  ascites
 RAK-9G7 (SDS-sens)    3-5 weeks

Monoclonal antibody is prepared as purified IgG in 100 microgram quantities, unless other arrangements are made. If current inventory is ascitic fluid or cryopreserved cells, we will estimate the time necessary to produce these particular antibodies. Please inquire for details and current prices.

RICKETTSIA TYPHI MONOCLONALS

This collection used extracted rOmpB (protein) from Rickettsia typhi (Wilmington) as immunogen. The reactivities are mainly quite specific for R. typhi, with low-level to negligable reactivity to R. prowazekii.


CLONE           
 TARGET  X-REACTIVITY  AVAILABILITY
RT-10E7  rOmpB  
  3-5 weeks
 RT-10G10
  rOmpB  
  3-5 weeks
 RT-1C9  rOmpB  
  ascites
 RT-1H7  rOmpB
 3-5 weeks
 RT-2A10  rOmpB  
  3-5 weeks
 RT-2D6
  rOmpB  
  ascites
 RT-2E11  rOmpB  
  3-5 weeks
 RT-2F7  rOmpB  
  3-5 weeks
 RT-3C1  rOmpB  
  3-5 weeks
 RT-3C10  rOmpB    3-5 weeks
 RT-3D1  rOmpB  
  3-5 weeks
 RT-3E2
  rOmpB  
  3-5 weeks
 RT-3E3  rOmpB  
  3-5 weeks
 RT-3F11  rOmpB
 ascites
 RT-3G1  rOmpB  
  3-5 weeks
 RT-3G4  rOmpB  
  3-5 weeks
 RT-4A11  rOmpB  
  3-5 weeks
 RT-5E7  rOmpB  
  3-5 weeks
 RT-5G6  rOmpB  
  3-5 weeks
 RT-6A4  rOmpB    3-5 weeks
 RT-6A8  rOmpB  
  3-5 weeks
 RT-6B10
  rOmpB  
  ascites
 RT-6E6  rOmpB  
  3-5 weeks
 RT-6H3  rOmpB
 ascites
 RT-7A9  rOmpB  
  ascites
 RT-7C9
  rOmpB  
  3-5 weeks
 RT-7H11  rOmpB  
  ascites
 RT-7H2  rOmpB  
  3-5 weeks
 RT-8D7  rOmpB  
  ascites
 RT-8H3  rOmpB    3-5 weeks
 RT-9D11  rOmpB  
  3-5 weeks
 RT-9F11
  rOmpB  
  3-5 weeks
 RT-3E3  rOmpB  
  3-5 weeks
 RT-3F11  rOmpB
 3-5 weeks

Monoclonal antibody is prepared as purified IgG in 100 microgram quantities, unless other arrangements are made. If current inventory is ascitic fluid or cryopreserved cells, we will estimate the time necessary to produce these particular antibodies. Please inquire for details and current prices.

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